Floating solar panel park

Treball desenvolupat dins el marc del programa 'European Project Semester'.This Final Report is the culmination of a four month long design study on floating solar panel park feasibility in Vaasa, Finland. The Floating Ideas Team was tasked with coming up with a design that would not only work, but also make a profit. The team focused a lot of time on initial research, an iterative design process, and experiments to gather information that could not be found during the research phase. In this report, one can expect to find the major findings from research in many different areas such as location, panel design, flotation design, cooling techniques, and efficiency adding techniques. The first takeaway is that implementing floating solar parks in Finland would require adding efficiency techniques such as mirrors or concentrators. Second, how the panels are placed means a lot in a location so far north. Placing the panels far away from each other and horizontally will reduce the negative impact of shadows. And third, the rotation of the structure is important in increasing efficiency. Multiple axis tracking is not necessary, but tracking in the vertical axis can add a 50% increase in power generated. This research then lead into the defining of four initial designs which were eventually paired down into one. The largest factors leading to the change in design were the combination of rotation and anchoring methods, the flotation structure, and the structure required hold the panel modules together. In the end, the final design is a modular circular design with panels and mirrors to help add efficiency, approximately 37%. From there, an economic and environmental feasibility study was done and for both, this design was deemed feasible for Finland. With the design, detailed in this report, it would be possible to implement this and make a profit off of it, leading the team to believe that this should be implemented in places looking for alternatives for renewable energy production

Floating solar panel park

Treball desenvolupat dins el marc del programa 'European Project Semester'.This Final Report is the culmination of a four month long design study on floating solar panel park feasibility in Vaasa, Finland. The Floating Ideas Team was tasked with coming up with a design that would not only work, but also make a profit. The team focused a lot of time on initial research, an iterative design process, and experiments to gather information that could not be found during the research phase. In this report, one can expect to find the major findings from research in many different areas such as location, panel design, flotation design, cooling techniques, and efficiency adding techniques. The first takeaway is that implementing floating solar parks in Finland would require adding efficiency techniques such as mirrors or concentrators. Second, how the panels are placed means a lot in a location so far north. Placing the panels far away from each other and horizontally will reduce the negative impact of shadows. And third, the rotation of the structure is important in increasing efficiency. Multiple axis tracking is not necessary, but tracking in the vertical axis can add a 50% increase in power generated. This research then lead into the defining of four initial designs which were eventually paired down into one. The largest factors leading to the change in design were the combination of rotation and anchoring methods, the flotation structure, and the structure required hold the panel modules together. In the end, the final design is a modular circular design with panels and mirrors to help add efficiency, approximately 37%. From there, an economic and environmental feasibility study was done and for both, this design was deemed feasible for Finland. With the design, detailed in this report, it would be possible to implement this and make a profit off of it, leading the team to believe that this should be implemented in places looking for alternatives for renewable energy production

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Abstract Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic variation is understudied for blood lipids in large sample sizes. We now analyze genetic and blood lipid data in a high-coverage whole X chromosome sequencing study of 65,322 multi-ancestry participants and perform replication among 456,893 European participants. Common alleles on chromosome Xq23 are strongly associated with reduced total cholesterol, LDL cholesterol, and triglycerides (min P = 8.5 × 10−72), with similar effects for males and females. Chromosome Xq23 lipid-lowering alleles are associated with reduced odds for CHD among 42,545 cases and 591,247 controls (P = 1.7 × 10−4), and reduced odds for diabetes mellitus type 2 among 54,095 cases and 573,885 controls (P = 1.4 × 10−5). Although we observe an association with increased BMI, waist-to-hip ratio adjusted for BMI is reduced, bioimpedance analyses indicate increased gluteofemoral fat, and abdominal MRI analyses indicate reduced visceral adiposity. Co-localization analyses strongly correlate increased CHRDL1 gene expression, particularly in adipose tissue, with reduced concentrations of blood lipids

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele